Lightnovo

Application notes

Application note: miniRaman Spectrometer for Analysis of Honey and Syrups

Application note: miniRaman Spectrometer for Analysis of Honey and Syrups

The Lightnovo miniRaman spectrometer showcases its advanced capabilities in the analysis of honey and syrups, providing a compact and efficient solution for differentiating high-sucrose products like sugar syrups from low-sucrose or natural sweeteners such as honey. This application note demonstrates how miniRaman is a reliable tool for ensuring the authenticity and quality of liquid sweet food products.
Samples Analyzed with the miniRaman spectrometer:
  1. Natural Bee Honey: A late summer honey sourced from Denmark, with a sucrose content of ≤5%.
  2. Maple Syrup: A commercially available product made with natural sugar substitutes like sorbitol, erythritol, and steviol glycosides.
  3. Sweet Syrup: Another commercial syrup using the same natural sweeteners as maple syrup.
  4. Sugar Syrup: A homemade sucrose solution consisting of water and white sugar.

Using the miniRaman spectrometer, these samples were analyzed with minimal preparation, demonstrating its ability to differentiate between complex compositions and detect potential adulteration. This makes the miniRaman an essential tool for quality control and product authentication in the food industry.This makes the miniRaman an essential tool for quality control and product authentication in the food industry.

Application Note: Raman Spectroscopy of Over-the-Counter Pharmaceuticals and Supplements

Application Note: Raman Spectroscopy of Over-the-Counter Pharmaceuticals and Supplements

This Application Note highlights the power of Raman spectroscopy in analyzing and identifying over-the-counter medicines and health supplements, with the innovative miniRaman spectrometer.
Samples Analyzed
  • Whey Protein
  • Creatine Monohydrate
  • Vitamin C
  • Multivitamins
  • Ibuprofen
  • Paracetamol
Lightnovo’s miniRaman spectrometer, equipped with a high-precision contact probe and powered by Miraspec software, enables direct Raman spectroscopy analysis through plastic packaging. This innovative approach ensures rapid, non-invasive testing while delivering high-quality, reproducible results. The system achieved exceptional accuracy, with hit quality indices (HQI) above 97% for most tested samples.Key benefits of Lightnovo’s solution include:
  • Non-destructive analysis suitable for pharmaceutical and supplement testing.
  • Ease of use for both laboratory and field applications.
  • High sensitivity for reliable compound identification.

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Application note: In-vivo Skin Measurements with miniRaman Spectrometer

Application note: In-vivo Skin Measurements with miniRaman Spectrometer

The Lightnovo miniRaman spectrometer is a compact and efficient solution for non-invasive in-vivo skin measurements. Designed for high-precision analysis, it provides detailed insights into the molecular composition of the skin, from the surface to depths of up to 150 µm.
Samples and Results:
  • Skin Areas Analyzed: Finger, hand, and cheek at depths of 10–20 µm.
  • Raman Spectra Observed: Clear differentiation in water content across areas using CH (2800–3000 cm⁻¹) and OH (3100–3500 cm⁻¹) bands.
  • Application Example: Penetration of anti-sun cream (SPF30) was successfully measured.
The miniRaman spectrometer, paired with a high-NA immersion probe, achieves a signal-to-noise ratio (SNR) of 500:1 within a 1-second exposure time, demonstrating its capability for efficient, reproducible skin analysis.
This powerful miniRaman technology is ideal for skin diagnostics and studying the penetration and permeation of topical formulation

 

Application Note: miniRaman Spectroscopy for Analysis of Christmas Tree Needles

Application Note: miniRaman Spectroscopy for Analysis of Christmas Tree Needles

Discover how Lightnovo’s miniRaman spectrometers provide precise and efficient analysis of Christmas tree needles. By leveraging advanced Raman spectroscopy, this study demonstrates how shifting excitation wavelengths reduces fluorescence interference, enhancing spectral clarity.
Key Highlights:
  • Instrumentation: Analysis conducted using Lightnovo miniRaman 785 nm and miniRaman 820 nm spectrometers
  • Benefits: The advanced capabilities of the miniRaman spectrometers allow for clear, accurate data collection even in complex organic samples.
Lightnovo’s miniRaman technology showcases its versatility and precision, offering solutions for diverse applications, including detailed organic material analysis. This innovative approach ensures reliable results across various use cases.
Explore its potential today.
Application Note: Microplastics Detection in Seawater Using 2D Raman Mapping

Application Note: Microplastics Detection in Seawater Using 2D Raman Mapping

Lightnovo’s compact Raman microscopes provide an innovative and efficient approach to analyzing microplastics (MPs) in seawater. This advanced technology enables direct, on-site detection of MPs on filters, eliminating the need for additional sample preparation and ensuring fast, accurate results.
Samples Analyzed:
  • Seawater Collection: A 10-liter sample from the Mediterranean Sea was filtered using a silicon membrane, and the residue was analyzed directly on the filter.
  • Raman Specifications: The system used a 532 nm laser to scan a 10×10 mm² field with a 2 µm spot size, capturing high-resolution spectral data across 600×600 points.
Lightnovo’s Raman microscopy offers a practical and effective solution for real-time microplastics detection. Its compact design and reliable performance make it suitable for both field monitoring and laboratory use, supporting environmental research and pollution control efforts.

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Application Note: Miniaturized Raman Microscope for Nutrient and Metabolite Quantification in Fermentation

Application Note: Miniaturized Raman Microscope for Nutrient and Metabolite Quantification in Fermentation

Lightnovo’s miniaturized Raman microscope is transforming the monitoring of microbial fermentation processes. Designed to measure nutrients, metabolites, and by-products in real-time, this compact technology ensures high precision and efficiency, making it an ideal solution for process control in industries like pharmaceuticals and biotechnology.
Samples Analyzed:
  • Nutrients and Metabolites: The system quantified critical components such as pHCA, glucose, MgSO₄, and Na₂HPO₄ during E. coli fermentation.
  • Correlated Analysis: Results from Raman spectroscopy showed strong alignment with HPLC data, confirming its accuracy and reliability for fermentation monitoring.
Lightnovo’s miniaturized Raman spectrometer offers a high-performance, cost-effective solution for monitoring and quantifying nutrients and metabolites. Its compact design and real-time capabilities make it a valuable tool for optimizing fermentation processes and ensuring consistent product quality.
Application Note: miniRaman Microscope for In-Vitro Bacteria Identification

Application Note: miniRaman Microscope for In-Vitro Bacteria Identification

Lightnovo’s miniaturized Raman microscope supports bacterial diagnostics by providing rapid, label-free bacteria identification and antimicrobial susceptibility testing (AST). This compact and accessible system delivers high accuracy and speed for advanced bacterial analysis.
Samples Analyzed:
  • Bacteria were cultured on agar plates and transferred directly to sterilized CaF₂ slides for consistent preparation.
  • The study targeted key bacterial strains, including E. coliMRSEMSSE, and S. lugdunensis.
  • Using Raman maps and machine learning, the system achieved 98.6% accuracy in bacterial classification with a reduced exposure time of 0.2 seconds per spectrum.
Lightnovo’s compact Raman technology offers precision, speed, and accessibility, setting a new standard for bacterial diagnostics. Discover how this innovative solution can enhance your research and diagnostic capabilities.
Explore its potential today.
Explore its potential today.

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